- • Fullerene C60 induces both genotoxicity and anti-genotoxicity in cadmium chloride exposed rats.
- • Strong anti-genotoxicity of virgin olive oil is reported.
- • Establishment of optimal settings for fullerene nanoparticles C60 and virgin olive oil biomedical applications is required.
In conclusion, molecular and cytogenetic studies showed that C60 and VOO exhibit anti-genotoxic agents against CdCl2-induced genotoxicity in rats. Further studies are needed to investigate the optimal conditions for potential biomedical applications of these anti-genotoxic agents.
Experimental design and genotoxic and anti-genotoxic effects of fullerene C60 and virgin olive oil against CdCl2 toxicity in rats.
The Health Dangers of Cadmium
Cadmium is a toxic metal that occurs naturally in the environment. Humans are exposed to cadmium mostly through plant-derived food. There is no safe margin of cadmium exposure and the need to lower human exposure is desperate. Cadmium produces a number of health problems and is a known carcinogen. In industry, it’s regulated by the Environmental Protection Agency (EPA) and it has a very low permissible exposure level.
Effects of Cadmium Exposure
Cadmium is of no use to the human body and is toxic even at low levels. The negative effects of cadmium on the body are numerous and can impact nearly all systems in the body, including cardiovascular, reproductive, the kidneys, eyes, and even the brain.
- Cadmium affects blood pressure. 
- Cadmium affects prostate function and testosterone levels. 
- Cadmium induces bone damage (Itai-ltai). 
- Exposure to cadmium can affect renal and dopaminergic systems in children. 
According to the US Environmental Protection Agency and the International Agency for Research on Cancer, cadmium induces multiple organ damage and one aspect of that is as a carcinogen.  Research by the National Institutes of Health, Department of Health and Human Services confirms cadmium is linked to human pancreatic cancer. 
CADMIUM CHLORIDE (CDC):